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Immunologic Disorders

 

The physicians at Allergy & Asthma Care are trained immunologists who  diagnose and treat the following immunologic disorders:

Allergic Bronchopulmonary Aspergillosis (ABPA)

Allergic Bronchopulmonary Aspergillosis (ABPA) is a complex condition that affects people with asthma and cystic fibrosis. It results from exposure to the fungus Aspergillus fumigatus, which leads to worsening airway inflammation and progressive damage to the lungs.

Allergic fungal sinusitis (AFS) 

Allergic fungal sinusitis (AFS) is believed to be an allergic reaction to aerosolized environmental fungi in an immunocompetent person. This is in contrast to invasive fungal infections that affect immunocompromised person.   Most patients with AFS have a history of allergic rhinitis and the exact timing of AFS development can be difficult to determine.  Thick fungal debris and mucus are developed in the sinus cavities and must be surgically removed so that the offending allergen is no longer present. Recurrence is not uncommon once the disease is removed. Anti-inflammatory medical therapy and immunotherapy are being employed to help prevent recurrence.

Common variable immune deficiency (CVID)

Common variable immune deficiency (CVID) is an immune deficiency that usually begins in young adulthood, resulting in increased susceptibility to infections and diminished responses to many vaccines. The most common infections are in the sinuses and airways  and include pneumonia and influenza.  Patients may experience meningitis or other systemic bacterial infections, recurrent eye or skin infections, or gastrointestinal symptoms related to compromised immune/gut function, including chronic diarrhea, malabsorption, or bloating. They may also have abnormal T-cell function and immune dysregulation, including lymphoid hyperplasia, gastrointestinal inflammation, autoimmune phenomena, and susceptibility to malignancy, especially lymphomas.

Hypogammaglobulinemia

Hypogammaglobulinemia is charactorized by abnormally low levels of all classes of immunoglobulins and is associated with increased susceptibility to infectious diseases.

IGA Deficiency

IGA Deficiency is the most common immune deficiency disorder. People with this disorder have low or absent levels of a blood protein called immunoglobulin A.

 

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